I was always of the opinion that ink doesn't affect the handling.
William Kalush, however, feels differently. If there's anyone I know who would know, it's him.
It's not just level of coverage - it's type of ink as well. Some inks, particularly if used in large amounts, will have what he says is a noteworthy negative impact on a card's slip and glide characteristics.
If you want more info - best to reach out to him. He runs the Expert Playing Card Company.